ACBS Researchers Identify Cell Surface Polymers Essential for Cell Shape and Involved in Host-Recognition

The laboratories of Dr. VK Viswanathan and Gayatri Vedantam recently published their findings on the importance of the Clostridium difficile cell wall glycopolymers PSII in bacterial cell shape, and cell surface polysaccharide deposition.  Mutants with decreased deposition are hypervirulent, possibly leading to altered cell surface antigen exposure. For further information, check out their paper: "A Clostridium difficile Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence", published in PLOS Pathogens in October, 2016